A good starting point is always a destination, and how to get there, how much will it cost, who all is going on this vacation, sometimes having a large party traveling together is advantageous, do they need a pet sitter, a nanny for the Children, how about a senior care giver for those who cannot travel? Would a vacation rental house or apartment be better than many hotel rooms, will they need immunizations before going and how long in advance do they need to get them, passports and visas, and information on medical conditions and medicines being taken, to take along. Also it is very important that all information on medical ID bracelets/necklaces, always be updated. Each person with a known disability or medical condition should have medical clearance before taking off on a vacation. Always have someone at home base who can access the information and be the liasion needed for medical care in time of emergency.